Sugammadex: clinical development and practical use / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 495-500, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-40684
ABSTRACT
Sugammadex is belonging to a new class of drugs the selective relaxant binding agents. Sugammadex can reverse residual paralysis by encapsulating free circulating non depolarizing muscle relaxants. The mains advantages of sugammadex when compared with conventional anticholinesterase agents are a much faster recovery time and the unique ability, for the first time, to reverse rapidly and efficiently deep levels of neuromuscular blockade. However it only works for reversal of rocuronium or vecuronium-induced neuromuscular blockade. When administered 3 min after rocuronium the use of a large dose (16 mg/kg) can even reverse rocuronium significantly faster than the spontaneous recovery after succinylcholine.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Paralisia
/
Succinilcolina
/
Inibidores da Colinesterase
/
Bloqueio Neuromuscular
/
Ciclodextrinas
/
Neostigmina
/
Fármacos Neuromusculares Despolarizantes
Idioma:
Inglês
Revista:
Korean Journal of Anesthesiology
Ano de publicação:
2013
Tipo de documento:
Artigo
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