Correlation of the left ventricular diastolic function and the heart rate variability in patients with acute myocardial infarction / 대한내과학회지

ABSTRACT

BACKGROUND: Reduced heart rate varaibility (HRV) after acute myocardial infarction (AMI) is an important risk factor for mortality and life-threatening arrhythmias. The correlation between the left ventricular (LV) diastolic function and autonomic balance expressed by HRV in patients with AMI was evaluated in this study. METHODS: A 2-dimensional and Doppler echocardiography and a 24-hour Holter monitoring were performed at 5th to 7th day after attack in 50 patients with AMI. The restrictive filling pattern of the LV diastolic function was defined by E/A ratio >2 or deceleration time (DT) of the mitral inflow Holter monitoring.

RESULTS:

DT correlated significantly with SDNN (r=0.53; p<0.001), CV (r=0.42; p=0.003), and SDANN (r=0.59; p<0.001). The patients with the restrictive filling pattern (n=10) had significantly lower SDNN (80+/-14 vs. 96+/-25 msec; p=0.044), CV (9.4+/-1.8 vs. 10.7+/-2.4%; p=0.012), and SDANN (61+/-11 vs. 79+/-24 msec; p=0.009) than those with non-restrictive filling pattern (n=40).

CONCLUSION:

Patients with the restrictive LV filling pattern after AMI had more reduced HRV than those with the non-restrictive filling pattern.