Mechanism, prevention, risk assessment and treatment in bisphosphonates induced osteonecrosis of the jaw / 대한치주과학회지
The Journal of the Korean Academy of Periodontology
;
: 1-8, 2009.
Artigo
em Coreano
| WPRIM
| ID: wpr-40954
ABSTRACT
PURPOSE:
Bisphophonates are drugs used to suppress osteoclastic activity and to treat osteoporosis, Paget's disease of bone and bone metastasis. The purpose of this report is to review the literatures on bisphopsphonates use that could affect bone healing and cause osteonecrosis of the jaws. MATERIALS ANDMETHODS:
Medline research was carried out to find relevant articles on bisphophonates and osteonecrosis of the jaw.RESULTS:
Oral administration of bisphopsphonates is reported to decrease the risk of adverse bone outcomes. On the contrary, IV bisphopsphonates is known to significantly increase the risk. Prevention of the osteonecrosis of the jaw is primary concern before usage. If the adverse bone reaction takes place, proper management and treatments are required to alleviate pain of patients and prevent further progression of necrosis.CONCLUSION:
Case reports of bisphosphonates induced osteonecrosis of the jaw are increasing. Dentists and physicians should be aware of the higher frequency of osteonecrosis of the jaw in patients receiving IV bisphopsphonates and be prepared to prevent and cope with adverse bone reaction.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteíte Deformante
/
Osteoclastos
/
Osteonecrose
/
Osteoporose
/
Fosfatidiletanolaminas
/
Oftalmoplegia
/
Administração Oral
/
Medição de Risco
/
Doenças Mitocondriais
/
Odontólogos
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
The Journal of the Korean Academy of Periodontology
Ano de publicação:
2009
Tipo de documento:
Artigo
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