The number and significance of CD+68 positive cells in hepatocellular carcinoma and cirrhosis tissue / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery
;
(4): 219-221, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-409884
ABSTRACT
Objective:
To investigate the number of CD+68 cells in hepatocellular carcinoma (HCC),paraneoplastic tissues,cirrhosis tissues and normal liver tissues and their clinical significance.Methods:
Surgical specimens from 60 cases of HCC,62 cases of cirrhosis and 23 cases of normal liver were investigated by immunohistochemical staining of CD+68with streptavidin-horseradish peroxidase detective system.Results:
(1)The order of the mean number of CD+68cells in the tissues from the highest to the lowest wasparaneoplastic,cirrhosis,normal liver and HCC tissues(P〈0.01);(2)The number of CD+68cells in the tissues decreased successively with the decrease of HCC differentiation (P〈0.05);(3)There was no relationship between the number of CD+68cells in HCC and its clinical TNM stage;(4)The number of CD+68cells in the cases with metastasis within 15 months was significantly lower than that without metastasis (P〈0.05).Conclusion:
The number of CD+68cells might be an important marker to estimate the immune status and a useful factor to predict the prognosis of HCC patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Journal of Current Advances in General Surgery
Ano de publicação:
2005
Tipo de documento:
Artigo
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