INVESTIGATION ON TUMOR ASSOCIATED NEUTRAL GLYCOSPHINGOLIPIDS / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army
;
(12): 157-159, 2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-410727
ABSTRACT
To investigate the roles of neutral glycosphingolipids (N-GSLs) in the development of tumor, tumor antigen expression and immunological evasion, the regularities of the expression of N-GSLs in human embryonic and neoplastic tissue were studied, the influence of N-GSLs in the growth regulation, immunological evasion and multidrug resistance(MDR) of tumor cells were analyzed. The tumor embryonic associated antigen CDH, tumor multidrug resistance associated N-GSLs CMH and neoplasm inhi-bitor globoside were found. The significance of N-GSLs synthesis inhibition and de-N-glycosylation in the reversion of MDR and tumor therapy was also partly disclosed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Medical Journal of Chinese People's Liberation Army
Ano de publicação:
2001
Tipo de documento:
Artigo
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