Diagnosis and treatment of 40 cases of hyperthyroidism in pregnancy / 第二军医大学学报

ABSTRACT

Objective: To study the diagnosis， treatm ent and outcome of infants in patients with hyperthyroidism in pregnancy. Methods: The levels of T3，T4，TSH，FT3，FT4 in 40 cases of hyperthyroid gravida and control group were measured before delivery, the r oute of delivery and the outcome of infants were studied, and the neonatal thyroid f unctions were evaluated by the levels of T3，T4，TSH in cord serum samples . Results: The levels of T3，T4，FT3，FT4 in non-treatm ent group were higher than that of treatment group and control(P<0.01); an i ncreased rate of forceps and cesarean in hyperthyroid gravida was seen compared with that in control group, about 90%(36/40); the body weights of infants in no n-treatment group were lower than that in treatment and control group. There wa s a case of neonatal hyperthyroidism in non-treatment group. Conclusion: Hyperthyroidism should be diagnosed and treated earlier and there is little side effects on the outcome of infants.