Immunohistochemical Analysis of Prostatic Basal Cell / 复旦学报（医学版）

ABSTRACT

Purpose To study immunohistochemical quality of prostatic basal cell(PBC). MethodsTherty-seven of basal cell of benign prostatic hypertrophy (BPH) were studied using routine HE stavningand En Vision immunohistochemical methods. Results The positive rate of 34βE12 in PBC were 100 %;but all of the PBC were negative with Vim and SMA; the positive expression of PsAP PSA in PBC were35% ;expression of ck in the PBC was 71% and the positive rate of S-100 in PBC was onty 13.5%.Conclusions The resuts suggest that high molecular weight keratin 34βE12 is a specific marker to PBC;PBC has ability to adenoid epithelia differentiation of prostate and hyperplasia itself. PBC play an importantrole in growth, hyperplasia and disease of prostate. The PBC unlike myoepithelia, the ability to myoepitheliadifferentiation is to go a step further controversial opinion.