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The Incidence of β-thalassemia Heterozygote Car rying α-thalassemia-1 Gene / 中山大学学报(医学科学版)
Journal of Sun Yat-sen University(Medical Sciences) ; (6): 11-13, 2001.
Artigo em Chinês | WPRIM | ID: wpr-412128
ABSTRACT
【Objective】 To investigate the incidence of β-th alassemia (β-thal) heterozygote carrying α-thalassemia (α-thal ) 1 gene in Guangdong area. 【Methods】 β-thal genes were screened by reve rse dot blotting (RDB). In β-thal DNA samples α-thal 1 genes were am plified using gap-PCR method. 【Results】43 α-thal-1 cases were identifi ed among the 500 β-thal traits. The rate is 8.6%. 【Conclusion】 In Guangd ong area the incidence of β-thal heterozygote carrying α-thal-1 gen e is 8.6%, which should be paid much attention in the genetic counselling and pr enatal diagnosis.
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de incidência Idioma: Chinês Revista: Journal of Sun Yat-sen University(Medical Sciences) Ano de publicação: 2001 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de incidência Idioma: Chinês Revista: Journal of Sun Yat-sen University(Medical Sciences) Ano de publicação: 2001 Tipo de documento: Artigo