γ-amino butyric acid transporter and epilepsy / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 261-263, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-412791
ABSTRACT
According to 5 different subtypes of γ-amino butyric acid transporter(GAT)in brain regions and subcellular distribution.GAT1 and GAT3 are closely related with occurrence and development of epilepsy.The abnormal expression of GAT or their function damaged contribute to hyperexcitable neurons In seizures.GABAergic inhibit circuit reduces and the down-regulation of GAT expression,primary up-regulation of GAT expression is a reactive changes or cause of epilepsy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Pediatrics
Ano de publicação:
2011
Tipo de documento:
Artigo
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