Notch3 signaling pathway and cerebrovascular diseases / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 461-465, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-415846
ABSTRACT
The Notch pathway is an evolutionarily conserved signal transduction pathway. It consists of a complex system of interaction. Its function is associated with the embryonic development and cell differentiation regulation. Studies in recent years have demonstrated that Notch pathway is associated with specific human diseases, in which Notch3 signaling pathway is closely associated with the nervous system development and the structural integrity of blood vessels. Notch3 mutation may cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Cerebrovascular Diseases
Ano de publicação:
2011
Tipo de documento:
Artigo
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