The function of hepatic oval cells under high glucose condition in vivo / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 604-606, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-416746
ABSTRACT
Rat hepatic oval cell model was induced by hyperglycemia and streptozotocin in vivo. Expression of insulin and mRNA expression of pancreatic transcription factors(Nkx6.1, PDX-1) were carried out. It showed that under high glucose, liver tissues were positive for insulin staining, the expression of Nkx6.1 and Pdx-1mRNA was significantly enhanced, and insulin-1mRNA was found to be expressed. The result suggests that under high glucose, hepatic oval cells can differentiate into insulin-producing cells.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Journal of Endocrinology and Metabolism
Ano de publicação:
2011
Tipo de documento:
Artigo
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