Correlation of parents' birth weight and fetal macrosomia / 中华全科医师杂志
Chinese Journal of General Practitioners
;
(6): 575-577, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-417152
ABSTRACT
To investigate relationship between birth-weight of parents and fetal macrosomia and its genetic susceptibility. A case-control study with 237 macrosomia and 257 normal birth-weight babies was conducted to retrospectively analyze their parents' birth weight and mothers' conditions during pregnancy. Multivariate non-conditional logistic regression analysis showed that risk of macrosomia increased with increase in maternal birth-weight (OR = 1. 707, 95% CI 1. 145 - 2. 545) and paternal birth-weight (OR = 1.979, 95%CI1.306 -2.998). Macrosomia is fetal obesity and related to multi-gene susceptibility with heritability of 74.48%. Maternal effect on macrosomia may come from her obesity gene and intrauterine condition, while paternal effect mainly exhibits by his obesity gene carriage.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Idioma:
Chinês
Revista:
Chinese Journal of General Practitioners
Ano de publicação:
2011
Tipo de documento:
Artigo
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