Recent studies of microRNA in fatty liver disease / 国际儿科学杂志

ABSTRACT

MicroRNA(miRNA) is a sort of noncoding RNA, containing 19-20 nucleotides, for regulating gene function at the post-transcription level. The discovery of miRNA opens a new window for the research of gene expression, which plays an important role in regulating the proliferation and death of cell, the differentiation of neurocyte, and ontogeny, etc. Recently, it has been found that the miRNA molecules is closely related to the formation of fatty liver disease. Studying the effects and mechanisms of miRNA and fatty liver disease may become a new breakthrough point for the therapy of the disease.