Analgesic, anti-inflammatory experiment of Chinese pine node / 国际中医中药杂志

ABSTRACT

Objective To observe analgesic and croton oil-induced ear swelling effect of Chinese pine node.Methods Acetic acid writhing method and water tail-flick method was used to observe the analgesic effect,croton oil-induced ear swelling method was used to research anti-inflammatory effect.Results The inhibition rate of 1.0 g/kg,0.5 g/kg,0.25 g/kg of Chinese pine node on mice writhing response induced by acetic acid was 54.0％,44.3％,38.1％,and the inhibition rate on croton oil-induced mouse ear swelling was 48.4％,14.7％,7.4％.But no obvious influence on mice water tail-flick pain threshold.Conclusion Chinese pine node has anti-inflammatory and analgesic effects.