Vitamin D and its receptor in the role of kidney disease / 国际儿科学杂志

ABSTRACT

Vitamin D is an important hormone.Its biological effect is mediated by intracellular vitamin D receptor-specific.In recent years,studies have shown that active vitamin D and its receptor can reduce the degree of the pathological changes of the glomerular and tubular interstitial fibrosis,decrease 24 hour urinary protein,reduce the mortality rate of cardiovascular diseases,and have protective effect on chronic kidney disease.This paper reviews progress of the vitamin D and its receptor in kidney disease.