Glycolysis abnormality in neoplasm cells and the targeted therapy / 国际肿瘤学杂志
Journal of International Oncology
; (12): 726-728, 2012.
Article
em Zh
| WPRIM
| ID: wpr-419364
Biblioteca responsável:
WPRO
ABSTRACT
Cancer cells display a decreased mitochondrial respiration along with an abnormal activation of glycolysis to satisfy the demand of the malignant growth even in the presence of oxygen.This phenomenon may be caused by mitochondrial dysfunction,hypoxia of microenvironment and the abnormal activation of upstream regulators of glycolysis pathway.Treatment targeted at the glycolysis pathway and its upstream regulators may provide a new therapeutic strategy of cancer.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2012
Tipo de documento:
Article