Matrix metalloproteinase-9 in the invasion and metastasis of colorectal cancer / 国际肿瘤学杂志

ABSTRACT

Matrix metalloproteinases-9(MMP-9) is an important gene in coloreetal cancer occurrence and development.MMP-9 can induce cell proliferation,angiogenesis and neoplasm infiltration,and then leads to coloreetal cancer invasion and metastasis.MMP-9 can not only play the role individually in coloreetal canccr invasion and migration,but also can cooperate with other genes.MMP-9 is a key protease in terminal metastasis of coloreetal cancer.