Efficacy of imipenem-cilastin sodium as subsequent therapy on peritoneal dialysis-related peritioniets / 中华肾脏病杂志
Chinese Journal of Nephrology
;
(12): 652-655, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-419950
ABSTRACT
Objective To evaluate the efficacy of imipenem-cilastin sodium as subsequent therapy on peritoneal dialysis(PD)-related peritonitis.Methods From January 2007 to December 2010,44 PD-related peritonitis patients in our hospital were enrolled in the study.These patients presented cloudy fluid after 3 days initial treatment,and bacterial culture was Gram-negative bacteria or negative.Thirteen peritonitis episodes were treated with ceftazidime,while 36 episodes with imipenem-cilastin sodium.Efficacy,outcome,pathogen and drug-resistance were analyzed retrospectively.Results The effective rates 2 d later of ceftazidime and imipenem-cilastin sodium were 23.1% and 72.2% respectively with significant difference (P<0.05).Gram-negative bacteria of ceftazidime and imipenem-cilastin sodium groups were 69.4% and 65.2% respectively without significant difference (P>0.05).The cure rates 3 weeks later of ceftazidime and imipenemcilastin sodium groups were 23.1% and 72.2% respectively with significant difference (P<0.05).Conclusion As subsequent therapy for PD-related peritonitis,imipenem-cilastin sodium can improve the cure rate.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Nephrology
Ano de publicação:
2011
Tipo de documento:
Artigo
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