Correlative study between dynamic lactic acid monitoring and pediatric critical illness score in pediatric intensive care unit / 中国医师进修杂志

ABSTRACT

ObjectiveTo explore the relationship between dynamic lactic acid monitoring and pediatric critical illness score (PCIS) and clinical significance.MethodsPCIS of 77 critically ill children admitted into pediatric intensive care unit (PICU) were recorded after hospitalization.According to PCIS,all the children were divided into extremely critical group (23 cases),critical group (32 cases),non-critical group (22 cases),according to prognosis,all the children were divided into surrival group (55 cases) and death group (22 cases).Blood concentration of lactic acid were detected.Differences in their lactic acid indexes (including lactic acid level after admission to PICU,peak lactic acid level) and PCIS were compared,their correlation and prognosis of critid death group(22 cases) cally ill children were analyzed.Results Lactic acid level after admission to PIC U [ (5.28 ± 3.69) mmol/L ] and peak lactic acid level [(8.54 ± 4.32 )mmol/L] in extremely critical group were significantly higher than those in critical group and non-critical group (P ＜ 0.05 ),but PCIS [ (65.79 ± 2.34) scores ] was significantly lower than that in critical group and non-critical group(P ＜0.05).Lactic acid indexes in death group were significantly higher than those in survival group (P ＜ 0.05 or ＜ 0.01 ),but PCIS was significantly lower than that in survival group (P ＜ 0.05 ).PCIS was negative correlated with lactic acid level (P ＜ 0.01 ).ConclusionsCritically ill children with elevated lactic acid indexes are worse and poorer prognosis.PCIS score can effectively evaluate children's condition and prognosis,and compared with lactic acid level linear correlation is existed.Dynamic lactic acid monitoring indexes are the good factors for the severe degree and predicting the prognosis of the critically ill children.