Effect of curcumin on serum gelatinases level in patients with unstable angina pectoris / 心血管康复医学杂志
Chinese Journal of cardiovascular Rehabilitation Medicine
;
(6): 277-279, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-423786
ABSTRACT
Objective:
To investigate effect of curcumin on serum gelatinases level in patients with unstable angina pectoris (UAP).Methods:
A total of 80 UAP patients admitted from January 2010 to September 2010 were enrolled and randomly divided into curcumin treatment group (n=40) and routine treatment control group (n=40). Serum levels of gelatinases [contain matrix metalloproteinase (MMP)-2 and -9] of the two groups were measured before and 30d after treatment.Results:
Compared with before treatment , after treatment, serum levels of gelatinases significantly decreased [MMP-2(52.64±6.77)ng/ml vs.(32.65±1.67)ng/ml,MMP-9(56.75±7.34)ng/ml vs.(35±1.88)ng/ml]in curcumin treatment group (P<0.01), and they were significantly lower than those of routine treatment control group[MMP-2(32.65±1.67)ng/ml vs.(37.78±2.76)ng/ml,MMP9(35±1.88)ng/ml vs.(40.23±1.95)ng/ml]],P<0.05.Conclusion:
Curcumin could decrease serum levels of gelatinases in patients with unstable angina pectoris, and possesses effect stabilizing coronary artery plaque.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of cardiovascular Rehabilitation Medicine
Ano de publicação:
2011
Tipo de documento:
Artigo
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