Diffusion-weighted Magnetic Resonance Image Findings in Clinically Diagnosed Creutzfeldt-Jakob Disease
Journal of the Korean Neurological Association
;
: 219-223, 2000.
Artigo
em Coreano
| WPRIM
| ID: wpr-42418
ABSTRACT
We report distinctive diffusion-weighted magnetic resonance image (DWI) findings in a 65-year-old man with clinically diagnosed Creutzfeldt-Jakob disease (CJD). Four weeks before admission he developed general weakness and febrile sense which were followed by progressive dementia, ataxia, and choreo-athetoid movement of the right hand. T2-weighted magnetic resonance image (MRI) showed subtle high signal intensities only in the left basal ganglia, whereas DWI demonstrated marked hyperintensities in multiple regions including the left basal ganglia and left cerebral cortex. Five weeks after the onset of symptoms, he was noted to have myoclonus and characteristic electroencephalographic changes consisting of periodic triphasic sharp waves. In our patient, high signal changes on the DWI preceded myoclonus and typical EEG findings, a result suggesting that DWI may be useful in the early premortem diagnosis of CJD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ataxia
/
Gânglios da Base
/
Córtex Cerebral
/
Síndrome de Creutzfeldt-Jakob
/
Demência
/
Diagnóstico
/
Eletroencefalografia
/
Mãos
/
Mioclonia
Tipo de estudo:
Estudo diagnóstico
Limite:
Idoso
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Ano de publicação:
2000
Tipo de documento:
Artigo
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