Hepatokines as a Link between Obesity and Cardiovascular Diseases
Diabetes & Metabolism Journal
; : 10-15, 2015.
Article
em En
| WPRIM
| ID: wpr-42465
Biblioteca responsável:
WPRO
ABSTRACT
Non-alcoholic fatty liver disease, which is considered a hepatic manifestation of metabolic syndrome, independently increases the risks of developing cardiovascular disease (CVD) and type 2 diabetes mellitus. Recent emerging evidence suggests that a group of predominantly liver-derived proteins called hepatokines directly affect the progression of atherosclerosis by modulating endothelial dysfunction and infiltration of inflammatory cells into vessel walls. Here, we summarize the role of the representative hepatokines fibroblast growth factor 21, fetuin-A, and selenoprotein P in the progression of CVD.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Doenças Cardiovasculares
/
Diabetes Mellitus Tipo 2
/
Aterosclerose
/
Selenoproteína P
/
Fígado Gorduroso
/
Alfa-2-Glicoproteína-HS
/
Fatores de Crescimento de Fibroblastos
/
Obesidade
Idioma:
En
Revista:
Diabetes & Metabolism Journal
Ano de publicação:
2015
Tipo de documento:
Article