Research progress of additives for improving therapeutic peptides and proteins stability in PLGA microspheres / 国际生物医学工程杂志
International Journal of Biomedical Engineering
;
(6): 185-188, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-425899
ABSTRACT
Microspheres made of poly-lactic-co-glycolic acid (PLGA) have been frequently proposed as drug delivery systems.A very significant challenge in the development of controlled PLGA releasing systems is the instability of drugs especially therapeutic peptides and proteins.Additional approaches,particularly the use of additives,are needed to optimize PLGA delivery of drugs.This article reviews the effects of additives,especially the effects of stabilizing protein during the preparation of PLGA microsphere and the sustained drug releasing processes.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Biomedical Engineering
Ano de publicação:
2012
Tipo de documento:
Artigo
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