Role of microRNA in pathogenesis, progression, diagnosis and treatment of hepatocellular carcinoma / 国际外科学杂志
International Journal of Surgery
;
(12): 485-488, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-426726
ABSTRACT
MicroRNA (miRNA) is a class of endogenous,single-stranded non-coding small RNA that contains 21 to 23 nucleotides and is widely distributed in eucaryon,miRNA plays an important regulatory role in cell proliferation,apoptosis,growth and development through the regulation of gene translation after transcription and expression,miRNA has a close relationship with pathogenesis and development of hepatocellular carcinoma.And in this process,part of miRNA acts as oncogenes or tumor suppressor genes.A number of miRNA,such as miR-30d,miR-221,miR-222 and miR-101,had been found to express abnormally in hepatoeellular carcinoma.Here we summarize the related progress in research of miRNA and hepatocellular carcinoma.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
Idioma:
Chinês
Revista:
International Journal of Surgery
Ano de publicação:
2012
Tipo de documento:
Artigo
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