Advanced research of Fascin protein expression in human tumor / 肿瘤研究与临床

ABSTRACT

Fascin is an actin-bundling protein that is normally expressed in mesenchymal tissue and the nervous system. Many recent studies have shown that fascin was highly expressed in many human tumors and played a significant role in tumor proliferation, invasion, and metastasis. Fascin expression is also an independent factor correlated with poor patient prognosis and decreased survival rate. Fascin can be explored as a new molecular target for cancer treatment,thus can improve tumor patients' prognosis.