Immunohistochemical Demonstration of Nerve Fibers of the Human Knee Synovium / 대한정형외과연구학회지
Journal of Korean Orthopaedic Research Society
;
: 10-15, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-42900
ABSTRACT
PURPOSE:
To demonstrate the presence of nerve fibers including nociceptive fibers in synovium of human knee joint using immunohistochemistry. MATERIALS ANDMETHODS:
10 Synovial membrane tissues of knee joint obtained from 5 cadavers were analyzed immunohistochemically using antibodies to protein gene product 9.5, betaIII-tubulin, substance P and calcitonin gene-related peptide (CGRP).RESULTS:
Many nerve fibers immunoreactive for protein gene product 9.5 and betaIII-tubulin were demonstrated in synovial folds of human knee joints. Also, immunostaining showed the presence of free nerve ending fibers immunoreactive for substance P and calcitonin gene-related peptide in synovium.CONCLUSION:
The presence of putative nerve fibers including nociceptive fibers in synovial folds supports a possible role for theses structures as source of knee joint pain.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Membrana Sinovial
/
Cadáver
/
Imuno-Histoquímica
/
Substância P
/
Peptídeo Relacionado com Gene de Calcitonina
/
Joelho
/
Articulação do Joelho
/
Anticorpos
/
Terminações Nervosas
/
Fibras Nervosas
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of Korean Orthopaedic Research Society
Ano de publicação:
2007
Tipo de documento:
Artigo
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