Effects of Maixuekang capsule on blood coagulation with different diseases / 国际中医中药杂志

ABSTRACT

Objective To investigate the effects of Maixuekang capsule on blood coagulation.Methods 50 patients with different diseases from cardiologic department of Chongqing First People's Hospital from 2011 May to 2011 September were selected.The changes of their blood coagulation function were observed after taking Maixuekang capsule.Results Activated partial thromboplastin time (APTT-sec) and activated partial thromboplastin ratio (APTT-ratio) in 84 ds [(35.64±3.07),(1.11±0.10)] after using the medicine showed no statistical difference compared with the value before taking the medicine [(35.29±3.32) before treatment),(1.10±0.10)] (P＞0.05); while coagulation zymogen activity (PT％),prothrombin normalized ratio (PT-INR),prothrombin ratio (PT-ratio),prothrombin time(PT-sec),fibrinogen (Fib),thrombin time (TT-sec),and thrombin ratio (TT-ratio) in 84 ds after using the medicine [(105.22 ± 11.69)％,(0.98 ±0.07),(1.00±0.05),(13.08±0.69),(3.37±0.74)g/L,(18.12±1.41),(1.07±0.08)] showed significant changes than before the treatment [(114.64±9.10) ％,(0.93±0.04),(0.94±0.03),(12.50±0.42),(3.66±0.59)g/L,(16.84±0.71),(0.99±0.04)] (P＜0.05).Conclusion Maixuekang capsule has anti-cogulant effect on patients.