Significance of microsatellite instability in colorectal cancer / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 935-938, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-429843
ABSTRACT
Microsatellite instability (MSI) is an important molecular mechanism in colorectal cancer's initiation and progression,which has significant clinical significance.MSI is a diagnostic biomarker for Lynch synchrome.Moreover,the clinical implication of MSI testing extends to the role of prognostic marker and predictive maker,due to the better outcome of patients with MSI positive colorectal cancer and a general lack of response to chemotherapy employing 5-fluorouracil.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Journal of International Oncology
Ano de publicação:
2012
Tipo de documento:
Artigo
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