FcγR gene polymorphisms in Kawasaki disease susceptibility and the efficacy of intravenous immunoglobulin therapy / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 77-80, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-430194
ABSTRACT
Fcgamma receptors family conclude three groups(CD64、CD32、CD16),of which FcγR Ⅱa,Ⅱb,Ⅲb have Gene polymorphisms,for this reason they have an effect on affinity of FcγR to antibodies different,so FcγRⅡa,Ⅱb,Ⅲb are related to genetic susceptibility and IVIG treatment response.The Gene subtype of FcγR Ⅱ a is considered to be the susceptibility genes of KD.Polymorphisms of FcγRs were intimately connected to pathogenesis,coronary artery impairment and disease prevention of Kawasaki disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Pediatrics
Ano de publicação:
2013
Tipo de documento:
Artigo
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