Clinical Efficacy of Shenlingbaizhu Decoction on Immune Status in Patients with Ulcerative Colitis / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 3391-3393, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-430667
ABSTRACT
Objective To explore clinical efficacy of Shenlingbaizhu decoction on immune status in patients with ulcerative colitis(UC).Methods 60 patients with UC were selected and divided into control group and experiment group evenly and randomly.Control group received treatment of salazosulfapyridine,while experiment group received treatment of Shenlingbaizhu decoction based on treatments of control group.Clinical efficacy,serum levels of IL-6 and IL-8,percentage of Treg cells in peripheral blood were observed and compared between two groups before and after treatments.Results Total clinical efficacy of experiment group was significantly higher than that of control group(P<0.05)(90.00% vs 76.67%);Serum level of IL-6 was decreased significantly in all patients(P<0.05),more significantly in experiment group(P<0.05)after treatment;Serum level of IL-10 increased significantly in experiment group after treatment(P<0.05);Percentage of Treg cells increased significantly in experiment group after treatment(P<0.05).Conclusion Combination therapy of salazosulfapyridine and Shenlingbaizhu decoction shows significantly better clinical effects than salazosulfapyridine alone,probably via regulating immune status.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS