CHEMOTHERAPY THROUGH SUPER-SELECTED INTERNAL ILIAC ARTERY INCUBATION ON 36 CASES OF ADVANCED MALIGNANT TUMORS IN GYNECOLOGY / 肿瘤

ABSTRACT

Objective　To study the effects of super-selected internal iliac artery incubation in the treatment of advanced gynecological malignant tumors. Methods　36 cases of advanced gynecological malignant tumors (16 ovarian carcinoma, 13 cervical carcinoma, 3 vaginal carcinoma, 2 endometrial carcinoma, 1 choriocarcinoma and 1 leiomyosarcoma of uterus) were treated with this method for 48 times. 31 of these 48 times were embolized in bilateral iliac arteries, 13,2 and 1 cases the inferior mesenteric artery, the hepatic proper artery and the ovarian artery were embolized respectively. Results　4 cases showed complete response, 23 showed partial response, no change in 5 cases and in the rest 4 cases the disease was still in progress. The main side effects were slight gastro-intestinal reactions and embolism symptoms but no incubation complication occurred. Conclusion　The super-selected artery of incubation will give high local density of chemotherapeutic drugs and low concentration in general circulation. The effects are better in cervical, endometrial and vaginal carcinomas than in ovarian carcinoma.