Correlation between P300 of auditory and age, sex in healthy people / 安徽医科大学学报

ABSTRACT

Objective　To investigate the relationship between P300 of auditory event-related potential (ERP) and age, sex in healthy people. Methods　Auditory P300 was tested in 60 healthy people of different ages and the results were analyzed by t-test and the linear correlation. Results　The peak-latency (PL) and amplitude (Amp) of P300 were significantly different between the less than 59-year-old group and the more than 60-year-old group. For all subjects tested, age had positive linear correlation with PL of P300 and negative linear correlation with Amp of P300. There is no significantly sex difference in healthy people. Conclusion　There is influence of age on auditory P300. The PL is increased and the Amp is decreased with aging.