Isolation and Identification of Two Taxane Diterpenoid Compounds / 中国药科大学学报

ABSTRACT

AIM　Taxane diterpenoid compounds are expected to be isolated from Taxus chinensis cell cultures. METHODS　Cell cultures were extracted with 95% alcohol, distributed by different solvents, isolated via column chromatography on silica gel and purified by crystallization. RESULTS AND CONCLUSION　Two taxane diterpenoid compounds were isolated from Taxus chinensis cell cultures for the first time.Their structures were identified as 14β-(2-methylbutyryl)oxy-2α,5α, 10β-triacetoxytaxa-4(20),11-diene(1) and 5α-(cinnamoyl)oxy-7β,9α,10β,13α-tetraacetoxytaxa-4(20),11-diene(2) respectively.