Expression of CD117, CD34 and Ki-67 in gastric stromal tumors and their significances / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 393-395, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-434333
ABSTRACT
Objective To investigate the clinicopathologic and immunohistochemical features of gastric stromal tumors.Methods A total of 105 cases with gastric stromal tumors were included in the study.The expression of cluster of differentiation 117 (CD117),cluster of differ entiation 34 (CD34),smooth muscle actin (SMA),S-100 protein and Ki-67 in gastric stromal tumors specimens was detected by immunohistochemistry.The clinico-pathologic features of gastric stromal tumors were also analyzed.Results Of 105 gastric stromal tumors specimens,90 were positive for CD117 [85.7 % (90/105)],98 positive for CD34 [93.3 % (98/105)],21 positive for SMA [20.4 % (21/105)],60 positive for Ki-67 [56.1% (60/105)],13 positive for S-100 [12.4 % (13/105)].Conclusion Combined detection of CD117 and CD34 can improve the diagnostic accuracy of gastric stromal tumors.The expression of Ki-67 can be used as a prognostic parameter for gastric stromal tumors as it is correlated with tumor size,risk and mitotic.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Cancer Research and Clinic
Ano de publicação:
2013
Tipo de documento:
Artigo
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