Analysis of pathogenic bacteria, drug resistance and risk factors in patients with vaginitis in Zhangjiakou area / 中国基层医药

ABSTRACT

Objective To investigate characteristics of pathogen distribution and drug resistance,and to analyze risk factors of the infection in patients with vaginitis in Zhangjiakou area.Methods Vaginal secretion specimen from 368 patients with vaginitis were collected and then processed by germiculture,identification and drug sensitivity tests.Risk factors of infection were identified among age,marriage history,first sexual intercourse age,education,childbearing history,abortion history,contraception,householding et al by single factor x2 analysis and Logistic regression analysis.Results Blastomyces albicans,ureaplasma urealyticum,escherichia coli,enterococcus faecalis and gardner vaginal bacteria listed top 5 of composition of infection rate in patients with vaginitis.Blastomyces albicans was sensitive to multiple antifungal agent; escherichia coli and gardner vaginal bacteria were resistant to multiple antibiotics but sensitive to imipenem;ureaplasma urealyticum was resistant to multiple antibiotics but sensitive to josamycin and clarithromycin;enterococcus faecalis was strongly resisted to SMZ and erythromycin.Age ranging from 31 ～40y,application of IUD,positive abortion history and first sex intercourse before 23y were identified as risk factors for infection in patients with vaginitis.Conclusion Infection characteristics and risk factors could be utilized as indicators in considering treatment programs for patients with vaginitis.