Determination of chemical structure of antifungal Pityrosporum orbiculare ingredient from Alpinia galanga Swartz in Vietnam

ABSTRACT

Greater galangal rhizomes have been used as medicinal herbs to treat pityriasis versicolor and other diseases. By using a premilinary examination from TLC and the antifungal activity against Pityrosporum orbiculare, a new component was extracted from rhizomes of Alpinia galanga Swartz in Vietnam. The chemical structure of this component was determined by GC-MS and 1H & 13C NMR. Galangal acetate was a colorless, pungent and oily liquid. It showed the antifungal activity against P. orbiculare with MIC = 0.25 ml/ml