Signiifcance of epileptiform discharges in anti-epileptiform drug therapy and prediction of relapse Reviewer / 临床儿科杂志

ABSTRACT

EEGs performed for new-onset seizures show epileptiform discharge in approximately 18% to 56% of children and 12%to 50%of adults. EEG is the most commonly used means of neurological examination for epilepsy. Speciifc EEG abnormalities help characterize the seizure type and epilepsy syndrome, which allows more informed decisions regarding therapy and more accurate prediction of seizure control and ultimate remission. In certain cases, the EEG may detect more subtle seizures, including absence, myoclonic or partial seizures. In the therapy of epilepsy, the effect of different antiepileptic drugs on the inhibition of epileptiform discharges is different. Epileptiform discharges play a very important role in the prediction of recurrence and the decision to remove antiepileptic drugs.