Detection of Chlamydia trachomatis by PCR with reactive arthritis

ABSTRACT

Chlamydia trachomatis has been shown to induce reactive arthritis in people, especially after sexually acquired genitourinary infection. To determine the connection between Chlamydia trachomatis with reactive arthritis, in this study we examined antigen Chlamydia trachomatis lipopolysarcaride. Antibody IgG, and DNA of chlamydia trachomatis were investigated in samples (urine, serum, and synovial fluid) from 52 patients were diagnosed and treated in Rheumatology Department, Bach Mai Hospital from August 2001 to August 2003. As results we found that 38.5% urine samples positve with antigen LPS. Antibody IgG positive in 44.2% of serum samples and in 34.6% of synovial fluid samples. Special DNA of Chlamydia trachomatis was detected in 53.2% of synovial fluid samples and in 42.2% of urine samples positive. This results will contribute to determine the role of DNA-Chlamydia trachomatis in reactive arthritis diagnosis.