Recent advances in molecular targeted therapy and expression of iodine uptake relative protein in papillary thyroid carcinoma with BRAFV600E mutation / 中华内分泌代谢杂志

ABSTRACT

Type-B RAF (BRAF) gene is one of the most popular genes of thyroid carcinoma in recent studies,and its mutation has significant relationships with the occurrence,development,treatment,and prognosis of papillary thyroid carcinoma(PTC).The influence of BRAFV600E mutation on the expression of iodine uptake relative proteins in PTC cells and the value of molecular targeted therapy with BRAFV600Einhibitors in the clinical treatment of PTC in the future were summarized in this review.