The distribution and drug resistance analysis of escherichia coli in clinical specimens / 中国医师进修杂志

ABSTRACT

Objective To analyze the distribution and drug resistance of Escherichia coli which separated from clinical.Methods Collecting the bacteria specimens to separating and training Escherichia coli,and then screening and monitoring drug susceptibility by The Dark Horse Microbial Analysis System,from January 2010 to July 2011.Results The Escherichia coli 486 strains which separated from clinical,the male 297 cases,female 189 cases,secretion separation 236 strains was the highest rate (48.56％),sputum 165 strains (33.95％),urine 39 strains (8.02％),and the rest of the sample 46 strains (9.47％).ESBLs 198 strains,which resistance in 19 antibiotics were higher than Escherichia coli,and it was multiple antibiotic resistance such as Aminoglycoside,Quinolone etc; Escherichia coli strains were sensitive to imipenem.Conclusion Escherichia coli which separated in surgery,respiratory tract,and urinary had a large proportion,and Resistance of Escherichia coli was serious,we should according to the Drug sensitivity of Escherichia coli,choose reasonable application of antibiotics,especially the ESBLs strains.We should strengthen the resistance testing,to provide reference for clinical rational drug use.