Application of propofol combined with sub-anesthetic dose of ketamine in delivery analgesia / 中国基层医药

ABSTRACT

Objective To investigate the application of propofol combined with sub-anesthetic dose of ketamine in delivery analgesia.Methods 120 cases were randomly selected and divided into two groups.Control group included 60 cases who were given PCEA and the observation group included 60 cases who were given propofol combined with subanesthetic dose of ketamine before PCEA.Results The VAS scores of two groups had no significant difference(all P ＞0.05).The rate and extent of itching of observation group were significantly lower than control group (P ＜ 0.05).Cesarean section rate and the time of the birth process,the Apgar score of two groups had no significant differ ences (all P ＞ 0.05.Total satisfaction rate of observation group was significantly higher than control group (P ＜ 0.0 5).Awakening time of observation group was (12.1 ± 3.1) min and control group was (13.8 ± 3.5) min.Awakening time of observation group was significantly lower than control group (P ＜ 0.05).Conclusion Propofol combined with subanesthetic dose of ketamine in delivery analgesia can reduce the adverse reactions.It is safe and reliable.