Sulfasalazine-induced Reversible Leukoencephalopathy
Journal of the Korean Neurological Association
;
: 218-221, 2010.
Artigo
em Coreano
| WPRIM
| ID: wpr-43853
ABSTRACT
A 50-year-old woman presented with a 4-day history of apathy, perseveration, and confusion. These symptoms appeared 16 days after she had started taking sulfasalazine for rheumatoid arthritis. Brain MRI showed bilateral symmetrical discoid lesions involving the corona radiata. She fully recovered 7 days after stopping the medications. Follow-up brain MRI revealed remarkable improvement of the lesions. The pathomechanisms related to sulfasalazine-induced leukoencephalopathy may be demyelinating processes due to impaired T-cell-mediated immunity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artrite Reumatoide
/
Sulfassalazina
/
Encéfalo
/
Seguimentos
/
Leucoencefalopatias
/
Apatia
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Ano de publicação:
2010
Tipo de documento:
Artigo
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