Roles of SIRT1 in tumorigenesis and tumor progression / 国际肿瘤学杂志
Journal of International Oncology
; (12): 902-904, 2013.
Article
em Zh
| WPRIM
| ID: wpr-439047
Biblioteca responsável:
WPRO
ABSTRACT
Silent information regulator 1 (SIRT1) is a kind of histone deacetylase which dependents on nicotinamide adenine dinucleotide.It is involved in the occurrence and development of tumors.Data show that SIRT1 is highly expressed in many tumors,such as gastric cancer,breast cancer,prostate cancer and so on.On the other hand,the expression of SIRT1 is lower in many other types of tumors,including glioblastomas,bladder cancer,ovarian cancer and so on.Therefore,the role of SIRT1 in tumor formation process is still uncertain and controversial.
Texto completo:
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Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2013
Tipo de documento:
Article