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Ductal carcinoma in situ of the breast, report of 430 cases / 中华普通外科杂志
Chinese Journal of General Surgery ; (12): 857-860, 2013.
Artigo em Chinês | WPRIM | ID: wpr-439335
ABSTRACT
Objective To explore the clinical characteristics,treatment and prognosis of ductal carcinoma in situ of the breast.Methods We retrospectively analysed 430 patients with a diagnosis of DCIS in Cancer Hospital of Tianjin Medical University from January 1991 to December 2005,to evaluate the clinical characteristics,treatment and prognosis.Results Overall survival rate of 430 patients was 94.9% (408/430).10 cases died of breast cancer recurrence,7 for local recurrence,3 for metastsis.Tumor size,TNM stages and structural pattern of pathlogy were prognosis impacting factors (P < 0.05).The 5-year survival rate for combination radiotherapy and breast-conserving surgery group was 100%,and 10-year survival rate was 97.1%,comparing traditional modified radical mastectomy 5-year survival rate of 98.3%and 10-year survival of 96.7% (P > 0.05).The overall survival rate of surgery alone group (89.9%) was lower than the post-operative comprehensive treatment group (96.8%),(P < 0.05).Conclusions Treatment of DCIS should be based on primary tumor's clinical stage and histologic characters.Breast-conserving surgery enjoys the same outcome as traditional modified radical mastectomy.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico Idioma: Chinês Revista: Chinese Journal of General Surgery Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico Idioma: Chinês Revista: Chinese Journal of General Surgery Ano de publicação: 2013 Tipo de documento: Artigo