Relationship between polymorphisms of CX3CR1 gene and coronary artery disease: a Meta-analysis / 基础医学与临床
Basic & Clinical Medicine
; (12): 1170-1173, 2009.
Article
em Zh
| WPRIM
| ID: wpr-440615
Biblioteca responsável:
WPRO
ABSTRACT
Objective To find whether CX3CR1 V249I and T280M are associated with CAD. Methods Database in English and Chinese, including PUBMED, EMbase, were searched to get the case-control studies on the associa-tion between V249I, T280M and CAD. Results Six studies were reviewed. The pooled OR of V249I compared to wild type allele was OR =0. 85(95% CI =0. 67 ~ 1. 08,P >0. 05). The pooled OR of T280M compared to wild type allele was OR =0. 82(95% CI =0. 70 ~ 0. 96, P < 0. 05). Conclusion The T280M is a protective factor of CAD, while the V249I is not associated with CAD.
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Índice:
WPRIM
Tipo de estudo:
Observational_studies
/
Systematic_reviews
Idioma:
Zh
Revista:
Basic & Clinical Medicine
Ano de publicação:
2009
Tipo de documento:
Article