Comparison and improvement of in predicting the short-term prognosis of transient ischemic attack between ABCD and ABCD2 scores / 中华老年医学杂志

ABSTRACT

Objective To compare the short term prognostic values between the four scores including ABCD,ABCD2,ABCD+ low density lipoprotein (ABCD+ LDL),ABCD2 + LDL after transient ischemic attack (TIA).Methods 235 TIA patients were evaluated according to ABCD score,ABCD2 score,ABCD + LDL score and ABCD2 + LDL score.The occurrence of cerebral infarction was observed at day 2 and 7.The predictive value was compared between the four scores by using receiver operating characteristic (ROC) curve.Patients were classified into 3 risk groupslowrisk group,moderate-risk group and high-risk group according to ABCD2 L score,and the stroke incidence was compared between the 3 groups by using x2 test.Results The area under ROC curves (AUCs) of ABCD、ABCD2、ABCDL and ABCD2L was 0.68 (95％CI0.59-0.76),0.71 (95％CI0.62-0.80),0.73 (95％CI0.65-0.82) and 0.77 (95％CI0.69-0.84) in predicting the risk of cerebral infarction at day 2,and were 0.73 (95％CI0.66-0.81),0.77 (95％CI0.70 0.84),0.80(95％CI0.74-0.87) and 0.83 (95％CI0.76-0.89) in predicting the risk of cerebral infarction at day 7 respectively.Patients were divided into 3 groupslow-risk group (score 0-2) (n =28),moderate-risk group (score 3-5) (n=143) and high-risk group (score 6-8) (n=45) according to ABCD2L score.There were significant differences in stroke incidence at day 2 and 7 between the 3groups (0％,9.1％ vs.32.8％,0％,11.9％ vs.56.3％,x2=26.15,58.87,both P＜0.05).Conclusions ABCD2 score is better than ABCD score in predicting the short-term prognosis of transient ischemic attack.Combining ABCD2 score with LDL can significantly increase the predictive value of ABCD2 score.