Advances in microRNA regulated hepatitis B virus X protein in the pathogenesis of hepatocellular carcinoma with hepatitis B virus infection / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
;
(12): 785-788, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-442984
ABSTRACT
MicroRNAs (miRNAs) are evolutionarily conserved small noncoding RNAs of-22 nucleotides that exist in a wide variety of organisms,including animals,plants and virus.Mature miRNAs are able to control gene expression at a post-transcriptional level,either by blocking mRNA translation or inducing their degradation.Hepatitis B virus X protein (HBX) is a 17000 protein that is implicated to play a crucial role in hepatocarcinogenesis.Recently,many studies have shown that HBX is associated with miRNA regulation,and is involved in regulating fundamental biological processes of tumor in cell proliferation,differentiation and apoptosis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo de etiologia
Idioma:
Chinês
Revista:
Chinese Journal of Laboratory Medicine
Ano de publicação:
2013
Tipo de documento:
Artigo
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