Clinical features of adefovir dipivoxil-induced Fanconi syndrome and hypophosphatemic osteomalacia / 中华内分泌代谢杂志

ABSTRACT

Adefovir dipivoxil (ADV) is commonly used as an anti-viral agent in the treatment of chronic hepatitis B,with a dose-and time-dependent nephrotoxicity.Clinical analysis was made in 4 patients with chronic hepatitis B who developed Fanconi syndrome and hypophosphatemic osteomalacia after long-term use of ADV (10 mg/d).