Diagnostic value of homocysteine in coronary heart disease / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 979-980, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-446256
ABSTRACT
Objective To study the diagnostic value of homocysteine (Hcy) in coronary heart disease(CHD) .Methods 102 CHD patients were collected as CHD group [15 cases of acute myocardial infarction (AMI) ,56 cases of unstable angina pectoris (UAP) and 31 cases of table angina pectoris (SAP)] and 100 healthy subjects were collected as control group .The level of Hcy was measured by enzymatic cycling assay and the levels of folic acid (FA) and vitamin B12 (VB12 ) were measured by microparticle chemoluminescence immunoassay .Results The Hcy levels of patients with AMI ,UAP and SAP were significantly higher than con-trol group (P<0 .01) .The levels of AMI group ,UAP group and SAP group were (24 .12 ± 5 .87)μmol/L ,(22 .56 ± 6 .13)μmol/L and (17 .42 ± 5 .23)μmol/L ,respectively .Not only in CHD group ,but also in control group ,the level of Hcy in men was signifi-cantly higher than that in women .Similarly ,the level of Hcy were significantly higher in current smokers compared with non-smok-ers as well as in older group compared with young group .There were significant negative correlations between Hcy and FA (r= -0 .62 ,P<0 .01) and VB12 (r= -0 .47 ,P<0 .01) .Conclusion Hyperhomocysteinemia is significantly associated with CHD .Hcy may be an marker for early warning CHD .
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
Idioma:
Chinês
Revista:
International Journal of Laboratory Medicine
Ano de publicação:
2014
Tipo de documento:
Artigo
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