The clinical value of serum tumor markers in diagnosis of colorectal cancer / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 1931-1932, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-450656
ABSTRACT
Objective To investigate the clinical application value of serum tumor markers CA72-4,CA125,CA19-9 and CEA in the diagnosis of colorectal cancer.Methods 4 serum tumor markers CA72-4,CA125,CA19-9 and CEA levels in 50 cases with colorectal cancer(group A),50 cases with benign colorectal lesions(group B) and 50 healthy subjects(group C) were determined by chemiluminescence immunoassay and then analyzed statistically.Results The CA72-4,CA125,CA19-9 and CEA in group A were (18.46 ± 1.28) μg/L,(81.20 ± 5.82) tμg/L,(90.34 ± 5.39) ku/L and (28.44 ± 2.65) μg/L,which were significantly higher than those in group B (t =8.21,8.82,7.99,8.42,P < 0.05) and group C (t =9.01,9.65,9.21,9.62,all P < 0.05) ; while the differences between group B and group C were not significant (P > 0.05).The CA72-4,CA125,CA19-9 and CEA testing positive rates were significantly lower than combined detection (x2 =7.62,9.04,7.79,6.05,all P < 0.05).Conclusion Serum tumor markers CA72-4,CA125,CA19-9 and CEA in the diagnosis of colorectal cancer have important clinical significance,and the combined detection can improve the accuracy of diagnosis of colorectal cancer,which has better clinical value.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
Idioma:
Chinês
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Ano de publicação:
2014
Tipo de documento:
Artigo
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